Martin Ulmschneider's Page (Homepage: TEMPO)

Martin Ulmschneider

Department of Physiology and Biophysics
University of California at Irvine
D340 Medical Sciences I
Irvine, CA 92697-4560

Voice: 949-824-6993
FAX: 949-824-8540
E-Mail:

Publications

M.B. Ulmschneider & J.P. Ulmschneider (2010). Implicit membrane models for peptide folding and insertion studies. In "Molecular Simulations and Biomembranes: From Biophysics to Function" Royal Society of Chemistry In press.
M.B. Ulmschneider, J.C. Smith & J.P. Ulmschneider (2010). Peptide partitioning properties from direct insertion studies. Biophys. J. Letter 98, L60-L62.
M.B. Ulmschneider, J.P.F. Doux, A.J. Killian, J.C. Smith & J.P. Ulmschneider (2010). Mechanism and kinetics of peptide partitioning into membranes from all-atom simulations of thermostable peptides. JACS 132, 3452-3460.
C.L. Wee, M.B. Ulmschneider & M.S.P. Sansom (2010). Membrane/toxin interaction energetics via serial multi-scale molecular dynamics simulations. JCTC 6, 966-976.
J.P. Ulmschneider, J.P.F. Doux, A.J. Killian, J.C. Smith & M.B. Ulmschneider (2009). Peptide Partitioning and Folding into Lipid Bilayers. JCTC 5, 2202-2205.
J.P. Ulmschneider & M.B. Ulmschneider (2009). United Atom Lipid Parameters for Combination with the Optimized Potentials for Liquid Simulations All-Atom Force Field. JCTC 5, 1803-1813.
J.P. Ulmschneider & M.B. Ulmschneider (2009). Sampling efficiency in explicit and implicit membrane environments studied by peptide folding simulations. Proteins 75, 586-597.
M.B. Ulmschneider & J.P. Ulmschneider (2008). Folding peptides into lipid bilayer membranes. JCTC 4, 1807-1809.
M.B. Ulmschneider & J.P. Ulmschneider 2008. Membrane adsorption, folding, insertion and translocation of synthetic trans-membrane peptides. Mol. Mem. Biol. 25, 245-257.
J.P. Ulmschneider & M.B. Ulmschneider (2007). Folding simulations of the transmembrane helix of Virus Protein U in an implicit membrane model. JCTC 3, 2335-2346.
I. Daidone, M.B. Ulmschneider, A. Di Nola, A. Amadei & J.C. Smith (2007). Dehydration-driven solvent exposure of hydrophobic surfaces as a driving force in peptide folding. PNAS 104, 15230-15235.
J.P. Ulmschneider, M.B. Ulmschneider & A. Di Nola (2007). Monte Carlo folding of trans-membrane helical peptides in an implicit generalized Born membrane. Proteins 69, 297-308.
M.B. Ulmschneider, J.P. Ulmschneider, A. Di Nola & M.S.P. Sansom (2007). A generalized Born implicit membrane representation based on experimental insertion free energies. Biophys. J. 92, 2338-2349.
J.P. Ulmschneider, M.B. Ulmschneider & A. Di Nola (2006). Monte Carlo versus molecular dynamics for all atom polypeptide simulations. J. Phys. Chem. B 110, 16733-16742.
M.B. Ulmschneider, A. Di Nola & M.S.P. Sansom (2006). Evaluating tilt angles of membrane-associated helices: Comparison of computational and NMR techniques. Biophys. J. 90, 1650-1660.
M.B. Ulmschneider, A. Di Nola & M.S.P. Sansom (2005). Properties of integral membrane protein structures: Derivation of an implicit membrane potential. Proteins 59, 252-265.
M.B. Ulmschneider, D.P. Tieleman & M.S.P. Sansom (2005). The role of extra-membranous inter-helical loops in helix-helix interactions. PEDS 18, 563-570.
M.B. Ulmschneider, D.P. Tieleman & M.S.P. Sansom (2004). Interactions of a transmembrane helix and a membrane: Comparative simulations of bacteriorhodopsin helix A. J. Phys. Chem. B 108, 10149-10159.
D.P. Tieleman, I. Shrivastava, M.B. Ulmschneider & M.S.P. Sansom (2001). Proline-induced hinges in transmembrane helices: Possible roles in ion channel gating. Proteins 44, 63-72.
M.B. Ulmschneider & M.S.P. Sansom (2001). Amino acid distributions in integral membrane protein structures. BBA 1512, 1-14.

A Brief Curriculum Vitae

2009- University of California at Irvine, USA (Marie Curie International Fellow)
2009 University of Utrecht, The Netherlands (Human Frontier Short Term Fellow)
2006-2008 University of Oxford, UK (Wellcome Trust International Fellow / Research Associate)
2003-2005 University of Rome 'La Sapienza', Italy (Wellcome Trust International Fellow)
2002-2003 Indian Institute of Sience, Bangalore, India (Wellcome Trust International Fellow)
2002 Ph.D. Biophysics, Laboratory of Molecular Biophysics, University of Oxford, UK
1998 BA Physics, University of Oxford, UK

Research interests

Developing advanced algorithms for atomic detail biomolecular simulations (see Hippo Software Package)
Combining experimental and computational techniques to study membrane protein structure and dynamics
Protein-bilayer interactions and the insertion, folding and assembly of membrane proteins
The mechanisms of antimicrobial, cell-penetrating and viral channel forming peptides